Can We Reprogram Aging?
Cell identity and the possibilities of rejuvenation, with Dr. Jose Polo.
Watch episodeTHE PODCAST WITH DR. GEORGE MURPHY
Longevity science.
Without the hype.
What does it really mean to age well? Explore the biology, question the claims, and discover what the evidence actually shows.
New to The ReProgram?Start with the two-minute introduction
A scientist’s perspective. A human conversation.Explore the show
Mechanism over marketing.Evidence over anecdotes.Trade-offs over hype.
THE EPISODE COLLECTION
Follow your curiosity.
Conversations with researchers and solo explorations of the science shaping how we think about aging.
6 featured episodes
Can We Slow Human Aging?
A conversation with Dr. Nik Schork about testing interventions in people.
Watch episode
Your Blood May Be Aging Before You Are
New blood cells, an older blood-making system, and the questions that follow.
Watch episode
Muscle and the Biology of Staying Capable
Looking beyond appearance to muscle’s role in everyday capacity and recovery.
Watch episodeCreatine for Longevity?
Muscle, brain, safety and the limits of the longevity claim.
Listen to episodeDoes New Research Change the Grade?
Revisiting the evidence as the longevity story develops.
Listen to episodeThere’s more to explore.Browse the full YouTube collection
A RECURRING SERIES
Big claims.
A closer look.
The Scorecard.
From familiar supplements to emerging therapies, George puts the promise alongside the evidence. What is plausible? What has been shown in humans? And what are the trade-offs?
THE QUESTIONS BEHIND THE GRADE
01
Does the biology make sense?
Start with the mechanism.
02
What happens in people?
Look for meaningful human outcomes.
03
What does it cost in risk?
Consider safety, access and uncertainty.
Grades are editorial assessments of evidence and context, not personal treatment recommendations. Stronger evidence can change the score.
MEET YOUR HOST
A scientist.
Always a student
of the evidence.
Dr. George Murphy brings the perspective of a working researcher to the conversation about living longer and healthier.
He is a Professor of Medicine at Boston University and a co-founder of the Center for Regenerative Medicine at Boston University and Boston Medical Center.
His research explores stem-cell biology, exceptional longevity, and resilience to age-related disease. On The ReProgram, he brings that curiosity to conversations with scientists—and to the claims we encounter every day.
More about George
George earned his doctorate in Molecular and Cellular Biology at the University of Oxford and completed postdoctoral training at Harvard Medical School and Boston Children’s Hospital. His laboratory uses human cellular models to investigate how some people resist age-related disease.
FROM THE MURPHY LABORATORY
The science behind
the questions.
At Boston University and Boston Medical Center, George and his team study regenerative medicine, exceptional longevity, and resilience to disease.
Visit murphylaboratory.com ↗
CELLULAR MODELS
Centenarians in a dish
A bank of induced pluripotent stem cells from exceptionally long-lived people gives researchers a renewable resource for studying longevity in human cells.
Explore the stem-cell bank ↗
AGING & THE BRAIN
The 100-year-old neuron
Converting blood cells directly into neurons offers a way to study cells that retain characteristics of their donors’ age.
Explore neuronal models ↗
PRECLINICAL RESEARCH
A clinical trial in a test tube
Patient-derived cell models help researchers investigate potential treatments across different tissues and genetic backgrounds before human trials.
Explore the research platform ↗THE REPROGRAM PERSPECTIVE
Understand aging.
Build resilience.
Knowledge is power.
Curiosity is the starting point. Evidence moves the conversation forward.
PRESS & CONVERSATION
Bring the science
to your audience.
For interviews, speaking inquiries, scientific commentary and conversations about the future of healthy aging.
KEEP ASKING BETTER QUESTIONS
Your next conversation
starts here.
Subscribe on your preferred platform and join The ReProgram.